From Islapedia

Betsy (fl. 1800), an American brigantine of Boston, carrying 10 guns and a crew of 19 men, under Charles Winship. She left Boston in 1799; was seized and detained at Valparaiso by the Spaniards, but was later released; and arrived Northwest Coast 1800. After trading on the Alaskan coast and in the vicinity of Queen Charlotte Islands she sailed southward to San Diego, where she remained from August 25 until September 4, 1800. Betsy was the first American vessel to visit San Diego, and was supposed to be engaged in illegal trade and prohibited sea-otter hunting.

» HOWAY, F. W. A List of Trading Vessels in the Maritime Fur Trade, 1785-1825. Limestone Press:Kingston, Ontario (1973)